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Triplet loss for Chromosome Classification
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Volume - 4 | Issue - 1 | march 2022

Triplet loss for Chromosome Classification
Pranshav Gajjar  , Pooja Shah, Akash Vegada, Jainish Savalia
Pages: 1-15
Cite this article
Gajjar, P., Shah, P., Vegada, A. & Savalia, J. (2022). Triplet loss for Chromosome Classification. Journal of Innovative Image Processing, 4(1), 1-15. doi:10.36548/jiip.2022.1.001
Published
28 February, 2022
Abstract

The analysis of chromosomes, known as karyotyping, is essential in diagnosing various human genetic disorders and chromosomal aberrations. It can detect a variety of genetic diseases and provide a deeper insight into the human body. However, the process of manual karyotyping is highly time-consuming and requires accomplished professionals with a deep understanding in the field. An automated process is thus highly desirable to assist cytogeneticists and mitigate the cognitive load procured during karyotyping. With that intention, a similarity learning approach is proposed in this paper using ‘Triplet Loss’ for procuring high-dimensional embeddings. The Offline Triplet Loss, Semi-Hard Online mining, and associated hyperparameters are thoroughly tested and explored, and the obtained embeddings are used to classify the images into their respective chromosome classes and Denver groups. A comparative analysis on various embedding-classifying algorithms such as Multi-Layer Perceptron (MLP) and Nearest Neighbours is also demonstrated in this paper, along with experiments on associated distance metrics. The proposed methodologies deliver a superlative performance when compared to a baseline Convolutional Neural Network (CNN), on a publicly available chromosome classification dataset.

Keywords

Deep Learning Triplet Loss Karyotyping Siamese Network Image Classification

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