Abstract
Early prediction of cardiovascular diseases has always been a significant challenge due to data privacy risks, non-interpretable outcomes, and demographic biases associated with current machine learning approaches. In this paper, CARE-XAI (Comprehensive AI Risk Evaluation with Explainable Artificial Intelligence) is presented as a novel framework that combines federated learning, fairness optimization methods, and explainable artificial intelligence to predict cardiovascular diseases based on multiple clinical modalities. CARE-XAI uses the UCI Heart Disease database as the fundamental clinical modality, along with simulated behavioral and wearable datasets to improve predictive accuracy. Federated learning using the FedAvg algorithm ensures privacy-preserving training in a decentralized manner without any leakage of sensitive information about patients. Fairness optimization with the help of AIF360 is used to counteract demographic biases, while model transparency is guaranteed through SHAP explanations. Experimental results show that CARE-XAI provides an accuracy score of 83.1% with 82.5% precision, 84.3% recall, and 0.881 AUC values, while also performing comparably well with centralized frameworks.
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Journal of Ubiquitous Computing and Communication Technologies